It is more of a bullet construction and sectional density issue than of caliber. To give a rather extreme example: If I load a 180 grain JHP bullet in my 460 S&W at maximum potential velocities (likely exceeding 2300 fps), which was designed for 45 ACP velocities....... it will fail miserably on any big game (hog, Whitetail, etc.). It may even come apart in flight, due to it’s thin jacket, as it was designed for velocities in the 900 to 1000 fps area....similar to a varmint bullet designed for a .222, fired at max. velocity from a 22-250.
Proper bullet construction “trumps” bullet diameter....bullet must be designed to perform under the parameters, designated for the desired use! memtb
Last edited by memtb; 12/29/18.
