Well Steve, a good buddy of mine uses his 22-250 on everything (coyotes ,deer,antelope) he truly believes from his experience that the cannelured 55 's come apart easier and sometimes actually separate at the cannuelure sometimes. I didn't have that happen yet that I could tell with the Hornadys but experienced that on a 4x5 whttl buck at about 225 yds with 55 gr cannelured Rem PSP bullets. Only makes sense that a non cannelured jacket has more structural integrity. As you know a sample of 1 doesn't tell you doodly but makes you wonder. MB
If that's what he believes, all the power to him. Shooting success has a lot to do with what's between your ears. If he feels that way, and is successful, then he's found his formula.
That bullet is classed by Hornady as a varmint bullet. Personally, I would not use it for deer. Its lighter construction may be the reason they come apart, especially if they strike bone.