Shoot a hard cast lead bullet or minimally expanding jacketed bullet, keep the shots within 100 yards and don't take any marginal shots. It's not a dead right there type of rig but I am confident it would do the trick. I had a Contender in 357 mag that shot 180gr bullets at 1650fps out of an 8" barrel with MP300 - that thing was stout and I have no doubt it would do the trick.

A true sportsman counts his achievements in proportion to the effort involved and fairness of the sport. - S. Pope