When assigned an article on a specific cartridge, I start by consulting the latest published data, noting what loads are noted for accuracy (more companies do that these days) along with highest velocity. Have found most rifle handloaders are still into the highest possible velocity, despite a few contrarians.( like that crazy seafire guy)
Then I test all the top-listed powders, with several different bullets. Often I play around with seating depth as well. The tests often agree with published results, but also sometimes don't. But in general, those powders provide the highest odds of a good, consistent load..
I start out with 4895 and 4198... if it won't shoot those for accuracy, I think the barrel might not be up to snuff...
