I had no issues with mixing glasses and scopes until about ten years ago as my eyeglass prescription for acute near-sightedness became more and more extreme. I now need scopes with rapid focus eyepieces with a wide range of adjustments, good eye relief and forgiving eyeboxes. The older Zeiss Conquest and the MeoPro 6x42 are examples of these scopes. I have noticed that some more recent scope that I have or have tried require minimal adjustment even for my eyeglass. These include the Leupold VX-R, the Tract Toric and the Nightforce SHV.