It's possible just as it is with a rifle, but you'll need to penetrate bone enough to hit the brain, or hit not just the spine, but the spinal cord. That's like hitting a string of yarn. Miss the cord by 1/4" and you may not drop them. and the tip of your broadhead must be almost exactly "point on" because bone will deflect an arrow, and you do not have even 1/4 the trauma effect you get from shattering/exploding bone, as you would get with even a low velocity bullet.

Archers are often enthralled with 300 FPS from an arrow, but to point out the facts here, that just about 1/3 the speed of a slow pistol bullet like a 45 auto. SUPER fast arrows are almost "in 1st gear" compared to even a slow pistol round. A standard 9MM from a 3" barrel is almost 4X faster. A 30-30 is 7-1/2 X faster.

So overall I'd think it's not a good idea for you to try ----------- unless you can hit a dine 100% of the time, and NO exceptions ever.....at the range you will shoot from.