I mainly shoot partitions of AB for deer and pronghorn and aim straight up the back of the leg, 1/3 way up. Usually catch the back of the scapula (not much meat there anyways), top of heart and both lungs. If im worried about a deer running into something nasty or onto private I will take a base of the neck shot over a shouler shot........On Elk I shoot A-frames or Etips and I aim high shoulder to try to break them down. I also keep shoooting until they are on the ground.
