For a bolt action 250 I highly recommend 35 gr. H4895 under a 100 grain Ballistic Tip.
I tried H4895, Varget and H4350 with 100gn bullets and H4350 gave the higher velocity in my 20 inch barrel on the Ultralight. I also had a 24 inch barrelled Model 54 in .250 Savage and H4350 gave the highest velocity as well. I loaded 39gn H4350 which was max but the latest data shows 40.5gn now so H4350 may have got a tad slower, or they may have loaded to a bit higher pressure.
