For HP's for self defense, Gold Dots in 185 or 230 gr are excellent choice & will usually feed in anything if the OAL is right.

For plinking & practice, I buy SWC's from Bayou Bullets; they're coated & the best I've found at a very reasonable price if you buy 1,000 or more at a time.

Power Pistol has been my go-to powder for the last few years in the 45 (as well as 9mm) but Bullseye, Unique, AA5, AA7, BE-86 & AutoComp are all good.

If I only had Unique, I'd not be unhappy, just not as clean as Power Pistol.

MM