I have shot a bunch of deer with the 110g Sierra Pro hunter.
two loads in my remington 700 worked well:
57g of R#17 with a federal 215 primer
58g of Win 760 with a 9 1/2 primer
Complete penetration on broadside lung shots which I really like with massive internal damage with these loads doing 3300 fps
Same loads with a Barnes ttsx
I seat the bullets .050 from the lands
The 110's are the most accurate in my rifle shooting clover leaf groups from a sporter rifle.