I use Redding T7 with 4 or five different turrets. I load for my siblings and they each have different calibers. I have dies, sizing, neck, bump, seating set up for each caliber on a die. If I want to reload for a specific gun, I just swap a turret. Everything is set up for that gun.
I do deprime on a separate Lee press, just to keep the gunk off the Redding.
