if you hit the brain, it doesn't matter what bullet is used. For many years, the biggest bear on record was taken by a single .22 LONG, from a rifle, to the temple at 5 yds or less. A little indian woman did this and then used her single shot rifle to put some insurance bullets into the the same spot. This guy takes them with a blowgun
https://www.youtube.com/watch?v=euf2kMefMYg


https://www.youtube.com/results?search_query=bear+killed+with+a+9mm
https://www.ammoland.com/2017/06/be...d-record-grizzly-and-more/#axzz67IXDgggo