If the 250 got a 10-twist post WWII the 243 would never have been invented
Except for the fact that almost all 243 ammunition is 100gr or less, and you can make 250-3000 ammunition that shoots well that's 100gr or less.
The 243 is more flexible in that it can handle many longer 100gr bullets than the 250-3000 can.. but I'm not sure the 250 would have kept the 243 at bay. Winchester marketing and all.
I do think if they'd switched to a 1 in 9 or 10 twist in the 30's, that it would have continued to sell far better than it did.