Good things are always said about the 35 Whelen... but I don't have one...LOL.
If it's a question of what you already have that works best, then maybe it would help to tell us what you have?
I do agree with some of the other comments though - your arbitrarily restricted question means there's not much value to the discussion. In the real world, if I need a bang-flop result, I'm going to take a CNS shot like high shoulder, rather than expecting a magic cartridge/bullet combo to do it with a lung shot.
