The two most common primers in my area are CCI and Remington. I've exclusively used both for many years.
I've swapped CCI 200 and Remington 9 1/2 primers on many loads and have not seen any change. I would note however that I have seen a noticable change in some loads when swapping from a non magnum to a magnum primer and now days thats the only change I try with primers
Since CCI primers seat harder I often use a 9 1/2 Remington and switch to a CCI when the 9 1/2 primer starts seating easier than I like. Gets some extra mileage out of the brass
Primers probably make a difference for a thousand yard benchrest shooter but for the average hunter my opinion is its mostly about finding the right powder and loading straight ammo
Good bullets properly placed always work, but not everyone knows what good bullets are, or can reliably place them in the field
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