I loaded up some 125 NBT for a friends 30-06, way back in '89. He was moving to Yakima WA and wanted a 'coyote load" he said. I told him it would work on anything they had around there! He shot a few called in coyotes and the following year he shot a Blacktail around 300yds ( he wasn't sure exactly) but he said it dropped. This was back when they were "softer", but I figured that the lighter weights had less soft lead in the nose and more jacket. They behaved well. I used a 308 and a 165 NBT on a big axis around 240yds and he rolled over too. However, in mid 90s I tried the 180 NBT from my first 300WM and what a mess it made, ha. I went back to Barnes in it.
