Between me and my brother, the .350 has accounted for more than a few coastal rosies, a whole pile of bears, and his has taken it's share of African game and a couple muskox. And, you get the cool factor of owning a .350. that would be my vote. BTW, mine are both Ruger m77, he has a couple Remingtons, a couple rugers, a mrc, and a custom win m70. We both prefer the rugers for some reason
