Didn't penetration tests show the 220 NPT out of a '06 penetrated as well as the 300 NPT out of a .375 H&H?
I'd go with the 220 NPT. Shouldn't be a long range shot, just need good penetration.
There are other choices, for sure.
DF
OlBlue shot a modest bear from just over the ridge in Terror Bay with a 300gr NPT. Bullet went full length in one butt cheek and exactly out of an earhole! And it did exactly no damage to the hide or skull!
