Never have found a reason to use a 1911 while actually big game hunting. I have used it for targets of opportunity in off season, but in this state any semi auto rifle or handgun is limited to 5 rounds in the mag and 1 in the pipe during center fire big game seasons. Hell if deer hunting I can’t even carry a G26 on me for a CCW weapon, I have to switch to a GP100. With that in consideration I would say that using my 41 Mag Blackhawk is more advantageous than buying a 1911 platform in 10mm. YMMV
