Pharmvet: I have a BUNCH of Ruger 10/22's and have used even more scopes on them (I am a notorious "scope switcher"!).
My favorite scope for a Ruger 10/22 is a Leupold 4x12 with A/O (adjustable objective) and fine Du-Plex reticle.
I have done most everything there is to be done with that set-up and done it VERY well, indeed.
Best of luck to you with whichever you choose - but I highly recommend an adjustable objective model of what ever scope you decide on.
Hold into the wind
VarmintGuy
