Originally Posted by BigNate
Using 120's and RL22 has been so effective I quit trying other stuff.


My experience as well. I've been using a 25.06 for 30+ years and a 120gr anything is no doubt pure deer poison and works great with RL22 in my experience. You mentioned the Nosler Partition and you can rest assured that you'll never go wrong with the Partition. I've never been able to get great accuracy with them myself but for the distances you mentioned they'll probably shoot just fine. My go to load is the Speer 120gr Hot-Cor and RL22 and I have harvested countless deer with that combination. Another good one is the Sierra 117gr Pro Hunter or Gameking. Any of the bullets mentioned will kill a deer I just personally like the heavier choices and have had excellent results on game using them.


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