We used both the 300 Gr Hornady BTSP and the 270 gr.Hornady on a number of plains game animals in Africa. The 270 grainer was as near perfect for the elk sized critters as you could get. The 300 grainer also worked very well..the difference is that we never recovered a 300 grain bullet-complete penetration- and we did recover a number of 270 grainers.
From that I'd guess the 300 grainer was pretty tough.
