We’ve had good luck, on “small” big game (antelope/deer) at longer (430 yards) ranges with TSX’s/TTSX’s with rifles of much larger caliber than generally used on a typical Whitetail! We always go for behind the shoulder shots.....less lost meat! True, they don’t kill quite like a conventional cup and core, with their rapid expansion and greater tissue damage and do in fact appear to debilitate a bit more slowly.... but are ultimately reliable to perform as designed! Just say’n! memtb