I thinking along the same line as Ranger but I would look at a Henry lever action in 357. Then load it up up 38 specials. Pretty simple pull the hammer back & shoot. Work the action & pull the trigger for a fallow up. Simple enough & they probably used a lever action in their younger years.

Now that I'm think about it--How about a circuit judge. It's a rifle not a pistol. Put 410Federal 000 buck shot in it. It can be use single action or double action. Or maybe a 410 pump action again with the Federal ammo.