The quote is "Oh, the humanity!". It's from the "WKRP in Cincinatti " episode where they had a turkey drop for thanksgiving. Les Nessman was covering the event, and the turkeys just kept falling. This caused Les a fair amount of distress. The line might could have been used earlier in a fairly well known disaster, but I'd be too young to know anything about that. It's a shame about the rifle, too.