Pharmseller,
I did almost exactly what your are asking to do with my Sako 85, I wanted a 280 AI, so to rebarreled my Sako with a Krieger Barrel - I did it during my last class of gunsmithing school, so I had to do it myself... but yes... it can be done.
AS THE GUYS SAID - Tikka’s are all long action, the only thing I would caution is if you get a 7.08 version, the heavy part of the barrel may not extend far enough to cover the neck of a 280.
Normally the chamber barrel profile sticks out past the neck area just a tad (with the exceptions of ultralight barrels) to give one protection..
I’d really really like a stainless Tikka in .280 Rem but they don’t make it. I don’t know Jack about converting rifles into different cartridges, so educate me. What are my donor options?
P