My 22-250 pdog load has long been 34.5 H4895 and 55BT. Averaged under 3/8” for 5 shots when that barrel was much younger. Throat is about gone and it’s about to get a new hart barrel. My brother has always used 55 vmax and Varget. The vmax seemed to be a bit more destructive but both make a real mess of the prairie rats. I might try the 53 vmax or nosler when I get a new barrel. I’ve got about 800-1000 55 BT’s left so I’ll probably use those up and probably be ready for a new tube.
Good luck, Ben.