Ipopum: I currently own and load for 14 (fourteen!) long heavy barrel Rifles in caliber 22-250 Remington.
Including one factory Remington 40X-B with the 27 1/4" heavy stainless barrel.
Of the powders you listed I would suggest the 4895 and the 50 grain bullets.
I also am a GREAT admirer of the Sierra 50 and 55 grain Blitz bullets for Colony Varmints (not the BlitzKings just the Blitz) they are cheaper, very accurate and devastating on Varmints from a 22-250 and a 220 Swift.
Long live the 22-250 Remington!
Hold into the wind
VarmintGuy
