I have shot a number of deer and antelope with both the 7mmRM and 280AI.
With both factory rifles and rifles built on my lathe.

I like the 140 gr Nos Bal Tip, Nosler brass, and IMR-4166,


280AI 56.2 gr 4166, 140 gr NBT or AB, 3.34," 67kpsi, 3100 fps

There is nothing noble in being superior to your fellow man; true nobility is being superior to your former self. -Ernest Hemingway
The man who makes no mistakes does not usually make anything.-- Edward John Phelps