I probably fall in that category most of the time. A really big mature buck where I hunt goes 160 on the hoof. I generally use a 30-06 with Hornady IL 180's. I've killed everything from Fox to 400 pound boar hogs with it during deer season and it's effective.

I do plan to go completely overkill at some point and I will either have a 9.3x62 or a 9.3x74.