My go-to hunting load for the .375 H&H is 72.5gr of RL-15 with the 270gr TSX. Brown bears don't like the TSX. Not even a little bit.
Depending on how cwh hooks you up with powder, I probably have some '15 I can spare, as well.
I've shot a fair amount of IMR 4064 out of my .338-06 and .375s, and it does a good job, too.
