Assuming that you don't currently have another in either caliber, get the .44 S&W. That is unless you are planning on using it as your primary elephant, or such, gun. If you really want something bigger, then go for it. But seriously, why would you want anything more than a heavy loaded .44? It can shoot bigger and badder loads than I care to. A 240-250 or so grain .44 slug loaded to 1100-1200 FPS is plenty for anything I would want to shoot. Call me a wuss, but anything much more than that is just painful to me. That is not the max load for a .44, so you have plenty more to go if you want. What I like about the .44 is that I can shoot .44 Russian, what I call my ".44 Russian +P", .44 Special, what I call my ".44 Special +P", and all of the various .44 Magnum loads up to "T-Rex killers". It's a pretty darn versatile caliber. I don't think you will have that much versatility with the other, but in fairness, I am really not that familiar with it. Nor, do I see any reason to be. JMHO,YMMV.
