Of those mentioned, there is no wrong answer, particularly the 280AI. I personally would lean towards something that has quality factory loads if you ever find yourself too busy to handload (yea, I know nothing is really available today). Because 30-06 is so under loaded by the factory’s, I’d lean away from it even though I love it. Personally, I’d go with one of the 300 mags. FWIW, I’ve always found Weatherby ammo to meet or exceed advertised velocities. If you go that route, make sure your throat has sufficient freebore. Finally, I’ve become a real fan of the WSM cartridges. My favorite of the bunch is the 270 flavor. Personally, I’d feel comfortable with 150s at 3100+ to 500yds on elk, but not further.
