The only problem I'd have with the 308 is it doesn't lend itself to using bullets over 165 grains as well as say...the 30-06.
That said, the 308 was the round of choice for our mountain caribou hunt guide in far northern BC when I was 13 (1960). Otto Elden of Chetwind BC carried a Savage 99 FW 308 with open sights as his rifle of choice. He liked how it carried, how fast it was to get pointed at critters, and how well it went into a saddle scabbard.
I believe he used Remington Core-Lokt 150gr ammo. He had used it on moose and grizzly and swore by it.
