I tried for this result this year for the first time & while my placement was a bit further back Roughly 3" The results were devastating instant death. In this case the cartridge was the 6mm Arc w a 108 gr Berger Elite hunter. Shot distance was 254 yards plus per laser range finder. Meat damage was minimal with this quartering away shot that took out the lower portion of the spine.
Simply will never know what would have happened If The shot would have been 2" lower. reason I am a bit concerned is the tissue damage was very minimal Even with the diagonal hit on the lower portion of the spine. Near as I can tell the bullet expansion was very minimal. Like said earlier instant Lights out on what I expect to have been a 300 lb'ish live weight deer..
