Hyaluronic acid. It's something that's been used in race horses for decades.
You might finally get to do that marathon, Wabi! LOL
Or the synthetic versions - Euflexxa, Synvisc, etc.
When the knee is shot, R&R.
I did Euflexxa first (three injections a week apart) then my insurance changed it to Mono Visc. ( one injection) They are all about the same. I have been doing them every 6 months for two years. The last one I had both knees done.
My Ortho doc says with some people they don't see much change. My initial injection took about two weeks to see any difference. I feel about a 75% reduction in pain in walking and general usage, but not in any twisting or carrying something heavy.That still hurts like heck. I still don' t walk very far. Maybe 300 yards.
When low pressure system or bad weather moves in, nothing much helps and they ache.
I also use a topical cream, Sombra ( Amazon). It comes in a cool and warm therapy gel. I also use a CBD cream called Ugly Butter that I get from a Big R farm store. It also has a day and night version. Both day versions have Capsacin in them which to me works as a stimulant. I can't use that.
I highly recommend the injections if you have bone on bone. At least give it a try.