I'm a lefty myself, as my young son is and pops was.
I grew up shooting mostly lever rifles as it seemed to be dads compromise for being left handed.
Today, I'm still shooting the browning BL 22 I received as a gift back in 1982/'83. My son is learning on it also today.
I love the idea of the bottom ejection on Browning's semi auto 22. Ambidextrous feature that's for sure. Neither the BL 22 or SA 22 from Browning is a low cost gun though.
I also wouldn't hesitate to purchase Ruger 10/22 sportster being a lefty.