I and others on my teams have killed a LOT of coyotes with a 243 with the 80g Sierra BT Blitz...amazing accuracy and a very loud WHOP sound when you connect on a coyote. We shot a hot load of IMR 4064 with the 80g at 3400 fps in custom barrels, 26", 12 Twist with very short freebore. 1/2" accuracy at 200 yards was the norm.

We also had stellar results with the 60g Sierra at 3850 with Win 760, coyotes never took a step, even when shot behind the diaphragm.