Not sure about your plans or direction , but with 150-180 gr bullets a 30-06 has proved quite lethal these last 116 years. That being said a handloaded .30-06 can be used for anything on this continent with careful loading .
A soft shooting 110-150 gr reduced load = a .30-30
A maxed out 150-185 gr load for general purpose
A maxed out 200 gr Nosler Partition or equal for the rest.
A 200-230 gr Berger out of an accurate .30-06 can do amazing things to 1200 Yds.
See Versatility............
