With the right bullet, that'll kill any big game animal in North America.

It's also about 100 fps more than 165's can be safely loaded to in a .30-06 with a 24" barrel, using newer powders. 100 fps is about what a typical 165 spitzer loses in about 40 yards, give or take a few yards.

“Montana seems to me to be what a small boy would think Texas is like from hearing Texans.”
John Steinbeck