I have used basically the same charge of IMR4227 as DaninAlaska uses with 235 Speers, but with the Hornady 220-grain flat-point. It basically duplicates a hot .38-55 or the .375 Winchester Big Bore, at around 2000-2100 fps. It generally hits about where full-power 300's hit (you can tweak the load a little to make it work) and not only is a good deer load, but works great on varmints as well.

JB

“Montana seems to me to be what a small boy would think Texas is like from hearing Texans.”
John Steinbeck