I'd smoke it in the Weber around 250 until you hit the stall. Approx 160 IT. Then I'd wrap in butcher paper, fat cap down, and place it in a foil pan, then into a 300 degree oven for the finish. Adjust temp as necessary. Probe tender is when it's done. Let it rest until it comes back down to 150-160 IT.

I'm also a fan of injecting briskets. I like Big Poppa Smokers Cattleprod.