I'd stay away from 150's unless you shoot a premium bullet. Backaches my buddy and I wanted "more speed" we loaded up 150's for my Win Mag and his RUM. Both ended up taking whitetails inside 50 yards the same day. Lots of meat damage, zero tracking required. I use 180s in my Win Mag now and don't use it for Whitetails other than one wide open farm I hunt.

"Life is not a journey to the grave with the intention of arriving safely in a well preserved body, but rather to skid in broadside, used up, worn out, bottle of Jim Beam in one hand and a .45 in the other, loudly proclaiming WOW-- What a Ride!"