The 30 06 and 375 Ruger are my go-to global rifle battery. For most hunts the 30 06 is the choice. But, where I hunt on my own property where there are no shots over 200 yards, and most closer to or under 100 yards, the 450 Bushmaster is what I take every time. The 450 BM starts falling on its face after 300 yards fast, perfect for my needs because I prefer the bullet to hit the dirt before it leaves my property. The kills are DRT every time. If I ever had to track, the blood trail would be obvious.