I have read somewhere that one of the U.S. military ammo factories produced 250 grain 30-06 loads that were issued to DEW Line radar sites and were intended to be used for killing polar bears that got into the buildings or posed a threat to the people working outside the buildings. I assume that they were intended to be fired in M1903s and M1 Garands. I don't recall having ever seen any of these cartridges, but some old guys who served on those isolated radar sites might have.