Dennis,
The 210 Nosler .338 will out penetrate the Nosler 250 gr. in the .338...I suppose because it is going faster and the partition works at both weights or perhaps the 210 partition blows off, but what ever the case the 210 Nosler is an awesome bullet in the .338 IMO...The 300 gr. Woodleigh is a real tough cookie to beat, its a hammer on anything and you get a lot of pass throughs with it, and the ones recovered are about like a baseball..I am not fond of the 225 Nosler as its neither fish nor fowl..The 250 Nosler will give you pretty mushrooms and does a pretty good job on anything, it may not penetrate like the 210 but it certainly does the job. Some folks like a bullet to expand all its energy in the animal and some like two holes..I personally lean towards two holes, but have seen some fantastic kills when a bullet stops on the off side skin..