I believe Eleanor O'Connor did her "one-shot safari" (17 animals with 19 shots) with the 160 Speer Hot-Core at 2650 or so from a 7x57.
I have been using the 160 Sierra GameKing at 2700 for a few years in the same cartridge and have yet to experience a jacket/core separation, at ranges from 100 to 375 yards. In fact all but one have exited. Haven't shot anything bigger than 250 pounds or so but gee....