I sailed a 154 grain Hornady RN from front to back of a whitetail doe a few years back. I shot her directly in the chest, and I found the exit out the back of her right ham. She ran about 60 yards or so. I was shooting a 7mm/08 that day, and if I remember correctly, it had a 21 inch tube. The Hornady interlock is a fine bullet.

"The number one problem with America is, a whole lot of people need shot, and nobody is shooting them."
-Master Chief Hershel Davis