Supercrewd: In the world of Varmint reloading I tend to disagree with your contention about the 22-250 Remington being the easiest cartridge to "get a good shooting load for".
I contend the 222 Remington and the 204 Ruger are definitely easier to obtain impressive accuracy with.
Don't get me wrong I love the accuracy from my various 22-250's but the 222 and the 204 are more inherently accurate in my opinion.
Long live the 22-250 Remington!
Hold into the wind
VarmintGuy