I have shot a number of cape buffalo with the 338 Win. I used solids mostly but I have used the 300 gr. Woodleighs also..They kill buffalo as well as the 9.3s or the .375 H&H..If there is any difference I would say that a buff shot with a solid from a .338 Win will run another 25 to 50 yards further than he might if shot with a 375 H&H..and the .338 is the full equal of a 9.3x62 and that is no light praise...

I would have no hesitation to shoot more buffalo with the .338.

My favorite buff calibers are the .416 or 404 and I like the Woodleigh 450 gr. bullets and/or Northfork cup points. In a monolithic I like GS Cusoms HPs. For whatever thats worth.